Publikationen

2024

• Ambrosio EM., Bailey CS., Unterweger IA., Christensen JB., Bruchez MP., Lundegaard PR., Ober EA.:
  LiverZap: a chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration
  In: Development 151 (2024), p. 1-10
  ISSN: 0950-1991
  DOI: 10.1242/dev.202217

2023

• Morgan KJ., Doggett K., Geng F., Mieruszynski S., Whitehead L., Smith KA., Hogan BM., Simons C., Baillie GJ., Molania R., Papenfuss AT., Hall TE., Ober EA., Stainier DY., Gong Z., Heath JK.:
  ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma
  In: eLife 12 (2023), Article No.: e73407
  ISSN: 2050-084X
  DOI: 10.7554/eLife.73407
• Unterweger IA., Klepstad J., Hannezo E., Lundegaard PR., Trusina A., Ober EA.:
  Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics
  In: Plos Biology 21 (2023), Article No.: e3002315
  ISSN: 1544-9173
  DOI: 10.1371/journal.pbio.3002315

2022

• Caviglia S., Unterweger IA., Gasiunaite A., Vanoosthuyse AE., Cutrale F., Trinh LA., Fraser SE., Neuhauss SC., Ober EA.:
  FRaeppli: A multispectral imaging toolbox for cell tracing and dense tissue analysis in zebrafish
  In: Development 149 (2022), Article No.: dev199615
  ISSN: 0950-1991
  DOI: 10.1242/dev.199615
• Dzementsei A., Barooji YF., Ober EA., Oddershede LB.:
  Foregut organ progenitors and their niche display distinct viscoelastic properties in vivo during early morphogenesis stages
  In: Communications Biology 5 (2022), Article No.: 402
  ISSN: 2399-3642
  DOI: 10.1038/s42003-022-03349-1

2021

• Ellman DG., Slaiman IM., Mathiesen SB., Andersen KS., Hofmeister W., Ober EA., Andersen DC.:
  Apex resection in zebrafish (Danio rerio) as a model of heart regeneration: A video-assisted guide
  In: International Journal of Molecular Sciences 22 (2021), Article No.: 5865
  ISSN: 1422-0067
  DOI: 10.3390/ijms22115865

2019

• Thestrup MI., Caviglia S., Cayuso J., Heyne RL., Ahmad R., Hofmeister W., Satriano L., Wilkinson DG., Andersen JB., Ober EA.:
  A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
  In: Nature Communications 10 (2019), Article No.: 5220
  ISSN: 2041-1723
  DOI: 10.1038/s41467-019-13149-7

2017

• Lonowski LA., Narimatsu Y., Riaz A., Delay CE., Yang Z., Niola F., Duda K., Ober EA., Clausen H., Wandall HH., Hansen SH., Bennett EP., Frödin M.:
  Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis
  In: Nature Protocols 12 (2017), p. 581-603
  ISSN: 1754-2189
  DOI: 10.1038/nprot.2016.165
• Wang S., Miller SR., Ober EA., Sadler KC.:
  Making It New Again: Insight Into Liver Development, Regeneration, and Disease From Zebrafish Research
  In: Kirsten C. Sadler (ed.): Zebrafish at the Interface of Development and Disease Research, Academic Press Inc., 2017, p. 161-195 (Current Topics in Developmental Biology, Vol.124)
  DOI: 10.1016/bs.ctdb.2016.11.012

2016

• Cayuso J., Dzementsei A., Fischer JC., Karemore G., Caviglia S., Bartholdson J., Wright GJ., Ober EA.:
  EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality
  In: Developmental Cell 39 (2016), p. 316-328
  ISSN: 1534-5807
  DOI: 10.1016/j.devcel.2016.10.009

2015

• Koltowska K., Lagendijk AK., Pichol-Thievend C., Fischer JC., Francois M., Ober EA., Yap AS., Hogan BM.:
  Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish
  In: Cell Reports 13 (2015), p. 1828-1841
  ISSN: 2211-1247
  DOI: 10.1016/j.celrep.2015.10.055
• Ober EA., Grapin-Botton A.:
  At new heights – Endodermal lineages in development and disease
  In: Development 142 (2015), p. 1912-1917
  ISSN: 0950-1991
  DOI: 10.1242/dev.121095

2014

• Dunworth WP., Cardona-Costa J., Bozkulak EC., Kim JD., Meadows S., Fischer JC., Wang Y., Cleaver O., Qyang Y., Ober EA., Jin SW.:
  Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos
  In: Circulation Research 114 (2014), p. 56-66
  ISSN: 1524-4571
  DOI: 10.1161/CIRCRESAHA.114.302452
• Markmiller S., Cloonan N., Lardelli RM., Doggett K., Keightley MC., Boglev Y., Trotter AJ., Ng AY., Wilkins SJ., Verkade H., Ober EA., Field HA., Grimmond SM., Lieschke GJ., Stainier DYR., Heath JK.:
  Minor class splicing shapes the zebrafish transcriptome during development
  In: Proceedings of the National Academy of Sciences of the United States of America 111 (2014), p. 3062-3067
  ISSN: 0027-8424
  DOI: 10.1073/pnas.1305536111
• van Impel A., Zhao Z., Hermkens DM., Roukens MG., Fischer JC., Peterson-Maduro J., Duckers H., Ober EA., Ingham PW., Schulte-Merker S.:
  Divergence of zebrafish and mouse lymphatic cell fate specification pathways
  In: Development 141 (2014), p. 1228-1238
  ISSN: 0950-1991
  DOI: 10.1242/dev.105031

2013

• Boglev Y., Badrock AP., Trotter AJ., Du Q., Richardson EJ., Parslow AC., Markmiller SJ., Hall NE., de Jong-Curtain TA., Ng AY., Verkade H., Ober EA., Field HA., Shin D., Shin CH., Hannan KM., Hannan RD., Pearson RB., Kim SH., Ess KC., Lieschke GJ., Stainier DYR., Heath JK.:
  Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis
  In: PLoS Genetics 9 (2013), Article No.: e1003279
  ISSN: 1553-7390
  DOI: 10.1371/journal.pgen.1003279
• Koltowska K., Apitz H., Stamataki D., Hirst EM., Verkade H., Salecker I., Ober EA.:
  Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis
  In: Development 140 (2013), p. 1912-1918
  ISSN: 0950-1991
  DOI: 10.1242/dev.093583

2012

• Schaub M., Nussbaum J., Verkade H., Ober EA., Stainier DYR., Sakaguchi TF.:
  Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network
  In: Developmental Biology 363 (2012), p. 128-137
  ISSN: 0012-1606
  DOI: 10.1016/j.ydbio.2011.12.025

2011

• Mas JC., Noël ES., Ober EA.:
  Chromatin modification in zebrafish development
  In: H. William Detrich III, Monte Westerfield, Leonard I. Zon (ed.): The Zebrafish: Genetics, Genomics and Informatics, Academic Press Inc., 2011, p. 401-428 (Methods in Cell Biology, Vol.104)
  DOI: 10.1016/B978-0-12-374814-0.00022-7
• Poulain M., Ober EA.:
  Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development
  In: Development 138 (2011), p. 3557-3568
  ISSN: 0950-1991
  DOI: 10.1242/dev.055921

2010

• Curado S., Ober EA., Walsh S., Cortes-Hernandez P., Verkade H., Koehler CM., Stainier DYR.:
  The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model
  In: Disease Models & Mechanisms 3 (2010), p. 486-495
  ISSN: 1754-8403
  DOI: 10.1242/dmm.004390
• Noël ES., Dos Reis M., Arain Z., Ober EA.:
  Analysis of the Albumin/α-Fetoprotein/Afamin/Group specific component gene family in the context of zebrafish liver differentiation
  In: Gene Expression Patterns 10 (2010), p. 237-243
  ISSN: 1567-133X
  DOI: 10.1016/j.gep.2010.05.002

2008

• Munson C., Huisken J., Bit-Avragim N., Kuo T., Dong PD., Ober EA., Verkade H., Abdelilah-Seyfried S., Stainier DY.:
  Regulation of neurocoel morphogenesis by Pard6γb
  In: Developmental Biology 324 (2008), p. 41-54
  ISSN: 0012-1606
  DOI: 10.1016/j.ydbio.2008.08.033
• Noël ES., Casal-Sueiro A., Busch-Nentwich E., Verkade H., Dong PDS., Stemple DL., Ober EA.:
  Organ-specific requirements for Hdac1 in liver and pancreas formation
  In: Developmental Biology 322 (2008), p. 237-250
  ISSN: 0012-1606
  DOI: 10.1016/j.ydbio.2008.06.040
• Osborne N., Brand-Arzamendi K., Ober EA., Jin SW., Verkade H., Holtzman NG., Yelon D., Stainier DYR.:
  The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish
  In: Current Biology 18 (2008), p. 1882-1888
  ISSN: 0960-9822
  DOI: 10.1016/j.cub.2008.10.061
• Shin CH., Chung WS., Hong SK., Ober EA., Verkade H., Field HA., Huisken J., Stainier DYR.:
  Multiple roles for Med12 in vertebrate endoderm development
  In: Developmental Biology 317 (2008), p. 467-479
  ISSN: 0012-1606
  DOI: 10.1016/j.ydbio.2008.02.031

2007

• Geisler R., Rauch GJ., Geiger-Rudolph S., Albrecht A., van Bebber F., Berger A., Busch-Nentwich E., Dahm R., Dekens MPS., Dooley C., Elli AF., Gehring I., Geiger H., Geisler M., Glaser S., Holley S., Huber M., Kerr A., Kirn A., Knirsch M., Konantz M., Küchler AM., Maderspacher F., Neuhauss SC., Nicolson T., Ober EA., Praeg E., Ray R., Rentzsch B., Rick JM., Rief E., Schauerte HE., Schepp CP., Schönberger U., Schonthaler HB., Seiler C., Sidi S., Söllner C., Wehner A., Weiler C., Nüsslein-Volhard C.:
  Large-scale mapping of mutations affecting zebrafish development
  In: BMC Genomics 8 (2007), Article No.: 11
  ISSN: 1471-2164
  DOI: 10.1186/1471-2164-8-11
• Jin SW., Herzog W., Santoro MM., Mitchell TS., Frantsve J., Jungblut B., Beis D., Scott IC., D'Amico L., Ober EA., Verkade H., Field HA., Chi NC., Wehman AM., Baier H., Stainier DYR.:
  A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos
  In: Developmental Biology 307 (2007), p. 29-42
  ISSN: 0012-1606
  DOI: 10.1016/j.ydbio.2007.03.526
• Shin D., Shin CH., Tucker J., Ober EA., Rentzsch F., Poss KD., Hammerschmidt M., Stainier DYR., Mullins MC.:
  Bmp and Fgf signaling are essential for liver specification in zebrafish
  In: Development 134 (2007), p. 2041-2050
  ISSN: 0950-1991
  DOI: 10.1242/dev.000281

2006

• Ober EA., Verkade H., Field HA., Stainier DYR.:
  Mesodermal Wnt2b signalling positively regulates liver specification
  In: Nature 442 (2006), p. 688-691
  ISSN: 0028-0836
  DOI: 10.1038/nature04888

2005

• Beis D., Bartman T., Jin SW., Scott IC., D'Amico L., Ober EA., Verkade H., Frantsve J., Field HA., Wehman AM., Baier H., Tallafuss A., Bally-Cuif L., Chen JN., Stainier DYR., Jungblut B.:
  Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
  In: Development 132 (2005), p. 4193-4204
  ISSN: 0950-1991
  DOI: 10.1242/dev.01970

2004

• Ober EA., Olofsson B., Mäkinen T., Jin SW., Shoji W., Koh GY., Alitalo K., Stainier DYR.:
  Vegfc is required for vascular development and endoderm morphogenesis in zebrafish
  In: EMBO Reports 5 (2004), p. 78-84
  ISSN: 1469-221X
  DOI: 10.1038/sj.embor.7400047

2003

• Field HA., Ober EA., Roeser T., Stainier DYR.:
  Formation of the digestive system in zebrafish. I. Liver morphogenesis
  In: Developmental Biology 253 (2003), p. 279-290
  ISSN: 0012-1606
  DOI: 10.1016/S0012-1606(02)00017-9
• Loosli F., Staub W., Finger-Baier KC., Ober EA., Verkade H., Wittbrodt J., Baier H.:
  Loss of eyes in zebrafish caused by mutation of chokh/rx 3
  In: EMBO Reports 4 (2003), p. 894-899
  ISSN: 1469-221X
  DOI: 10.1038/sj.embor.embor919
• Ober EA., Field HA., Stainier DYR.:
  From endoderm formation to liver and pancreas development in zebrafish
  In: Mechanisms of Development 120 (2003), p. 5-18
  ISSN: 0925-4773
  DOI: 10.1016/s0925-4773(02)00327-1

1999

• Münchberg SR., Ober EA., Steinbeisser H.:
  Expression of the Ets transcription factors erm and pea3 in early zebrafish development
  In: Mechanisms of Development 88 (1999), p. 233-236
  ISSN: 0925-4773
  DOI: 10.1016/s0925-4773(99)00179-3
• Ober EA., Schulte-Merker S.:
  Signals from the Yolk Cell Induce Mesoderm, Neuroectoderm, the Trunk Organizer, and the Notochord in Zebrafish
  In: Developmental Biology 215 (1999), p. 167-181
  ISSN: 0012-1606
  DOI: 10.1006/dbio.1999.9455